| Identification |
|---|
| BMDB Protein ID
| BMDBP02360 |
| Secondary Accession Numbers
| None |
| Name
| Biliverdin reductase A |
| Synonyms
|
Not Available
|
| Gene Name
| BLVRA |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in biliverdin reductase activity |
| Specific Function
| Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. |
| Pathways
|
- Porphyrin Metabolism
- Porphyrin-containing compound metabolism
- Protoheme degradation
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| Not Available |
| SNPs
| BLVRA |
| Gene Sequence
|
>891 bp
ATGAACACAGAGCCCGAGAGGAAGTTTGGCGTGGTGGTGGTGGGCGTCGGCAGAGCCGGC
TCCGTACGGATGCGGGACCTGCGGAATCCACACGCTTCCTCAGCGTTCCTGAACCTGATT
GGCTTCGTGTCCAGACGAGAGCTGGGGAGCATTGATGAGGTGCCGCAAATTTCTCTGGAA
GATGCTCTTTCCAGTCAAGAGGTCGAGGTTGCTTTTATCTGCAGTGAGAGCTCCAGCCAC
GAGGACTACATCAGGCAATTCCTGAATGCTGGAAAGCATGTCCTTGTGGAATACCCCATG
ACACTGTCTTGGGTGGCAGCTAAGGACCTGTGGGAGTTGGCCGAGCAGAAAGGGAAAGTC
TTGCATGAGGAGCATGTTGAACTCTTGATGGAGGAGTTTGCATTCCTGAAGAAAGAAGTG
GTGGGGAAGGACCTGCTGAAAGGGTCTCTCCTCTTCACAGCTGCCCCATTGGAAGAAGAG
CGGTTTGGCTTCCCTGCGTTCAGCGGCATCTCTCGCCTGACCTGGCTGGTCTCCCTCTTC
GGGGAGCTTTCTCTCGTATCTGCCACTTTGGAAGAGCGAAAGGAAGACCAGTATATGAAG
ATGACCGTGTGCTTGGAGACAGAGAACAAAAGCCCGCTGACCTGGATTGAAGAGAAAGCA
CCTGGCCTAAAGCGAAACAGACGCTTAAGCTTCCATTTCAGATCTGGGTCCCTAGAGAAT
ATGCCCAACGTAGGCATCAATAAGAATATTTTCCTGAAAGATCAGAATATATTTGTCCAG
AAACTCCTGGGCCAGTTCTCGGAAGAGGAGCTGGCTGCCGAGAAGAAACGCATCCTGCAC
TGCCTGTGGCTCGCAGGAGAGATCCAGAAACACTGCTGCTCAAAGCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 296 |
| Molecular Weight
| 33644.0 |
| Theoretical pI
| 6.12 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 225-245
- 253-273
- 281-301
- 320-340
- 361-381
- 383-403
- 417-437
- 450-470
|
| Protein Sequence
|
>BLVRA protein
MNTEPERKFGVVVVGVGRAGSVRMRDLRNPHASSAFLNLIGFVSRRELGSIDEVPQISLE
DALSSQEVEVAFICSESSSHEDYIRQFLNAGKHVLVEYPMTLSWVAAKDLWELAEQKGKV
LHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAAPLEEERFGFPAFSGISRLTWLVSLF
GELSLVSATLEERKEDQYMKMTVCLETENKSPLTWIEEKAPGLKRNRRLSFHFRSGSLEN
MPNVGINKNIFLKDQNIFVQKLLGQFSEEELAAEKKRILHCLWLAGEIQKHCCSKQ
|
| External Links |
|---|
| GenBank ID Protein
| AAI40587.1 |
| UniProtKB/Swiss-Prot ID
| A5D7K0 |
| UniProtKB/Swiss-Prot Entry Name
| A5D7K0_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC140586 |
| GeneCard ID
| BLVRA |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
