| Identification |
|---|
| BMDB Protein ID
| BMDBP02390 |
| Secondary Accession Numbers
| None |
| Name
| Cysteine and histidine-rich domain-containing protein 1 |
| Synonyms
|
Not Available
|
| Gene Name
| CHORDC1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in zinc ion binding |
| Specific Function
| Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 29 |
| Locus
| Not Available |
| SNPs
| CHORDC1 |
| Gene Sequence
|
>999 bp
ATGGCCCTGCTGTGCTACAACCGGGGCTGCGGCCAGCGCTTCGACCCCGAGACCAACTCT
GACGATGCTTGCACATACCACCCAGGCGTTCCAGTCTTTCATGATGCATTAAAGGGTTGG
TCTTGCTGTAAGAGAAGAACAACTGATTTTTCTGACTTTTTAAGTATCGTAGGCTGTACG
AAAGGAAGGCATAACAGTGAGAAGCCACCTGAGCCAGTCAAACCTGAAGTCAAGACTACT
GAGAAGAAAGAATTATCTGAGTTGAAACCCAAATTTCAGGAGCACATCATTCAGGCCCCT
AAACCAGTAGAAGCAATAAAAAGGCCAAGCCCGGATGAACCAATGACAAATTTGGAATTA
AAGATATCTGCCTCCCTAAAACAAGCACTTGATAAACTTAAACTGTCATCGGGGAATGAA
GAAAATAAGAAAGAAGAAGACAGTGATGAAATTAAGATTGGAACCTCATGTAAAAATGGA
GGGTGTTCAAAGACATACCAGGGTCCACAGAGTCTAGAAGAAGTCTGTGTATATCATTCT
GGAGTACCTATTTTCCACGAAGGGATGAAATACTGGAGCTGTTGTAGAAGAAAAACTTCT
GATTTTAATACATTCTTAGCCCAAGAGGGCTGTACAACAGGGAAACACATGTGGACTAAA
AAGGATGCTGGGAAAAAGGTTGTTCCGTGTAGACATGACTGGCATCAGACTGGGGGTGAA
GTCACCATTTCAGTATATGCGAAAAATTCACTTCCAGAGCTCAGCCAAGTGGTAGCAAAT
AGCACATTGTTAAATGTACACATTGTATTTGAAGGAGAGAAGGAATTTCATCAAAATGTG
AAATTATGGGGTGTGATTGATGTAAAGCGAAGCTACGTAACTATGACTGCAACAAAGATT
GAGATCACCATGAGAAAAGCTGAACCTATGCAGTGGGCAAGCCTTGAACTGCCTGCAGCC
AAAACCGAGGAAAAACAAAAGGAAGAGACAACGGAATGA
|
| Protein Properties |
|---|
| Number of Residues
| 332 |
| Molecular Weight
| 37427.0 |
| Theoretical pI
| 7.65 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Cysteine and histidine-rich domain-containing protein 1
MALLCYNRGCGQRFDPETNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIVGCT
KGRHNSEKPPEPVKPEVKTTEKKELSELKPKFQEHIIQAPKPVEAIKRPSPDEPMTNLEL
KISASLKQALDKLKLSSGNEENKKEEDSDEIKIGTSCKNGGCSKTYQGPQSLEEVCVYHS
GVPIFHEGMKYWSCCRRKTSDFNTFLAQEGCTTGKHMWTKKDAGKKVVPCRHDWHQTGGE
VTISVYAKNSLPELSQVVANSTLLNVHIVFEGEKEFHQNVKLWGVIDVKRSYVTMTATKI
EITMRKAEPMQWASLELPAAKTEEKQKEETTE
|
| External Links |
|---|
| GenBank ID Protein
| AAI14126.1 |
| UniProtKB/Swiss-Prot ID
| Q29RL2 |
| UniProtKB/Swiss-Prot Entry Name
| CHRD1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC114125 |
| GeneCard ID
| CHORDC1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
