| Identification |
|---|
| BMDB Protein ID
| BMDBP02473 |
| Secondary Accession Numbers
| None |
| Name
| IARS protein |
| Synonyms
|
Not Available
|
| Gene Name
| IARS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Translation, ribosomal structure and biogenesis |
| Specific Function
| Not Available |
| Pathways
|
- Protein Synthesis: Isoleucine
|
| Reactions
|
| Adenosine triphosphate + L-Isoleucine + tRNA(Ile) → Adenosine monophosphate + Pyrophosphate + L-Isoleucyl-tRNA(Ile) |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 8 |
| Locus
| Not Available |
| SNPs
| IARS1 |
| Gene Sequence
|
>3789 bp
ATGGTTCAACAAGTTCCAGAAAACATCAGTTTTCCTGCTGAAGAAGAGAAAATCTTGCAG
TTTTGGTCTGACTTTAATTGTTTCCAGGAATGCTTAAAGCAATCAAAACATAGGCCAAAA
TTTACCTTCTATGATGGGCCTCCTTTTGCAACTGGACTGCCTCACTATGGACATATACTT
GCAGGGACAATTAAAGATATAGTTACAAGATATGCTCACCAGAGTGGGTTTCACGTTGAC
AGAAGATTTGGCTGGGATTGTCATGGTTTACCTGTGGAATATGAAATTGATAAGACCCTG
GGAATCAGAGGACCAGAGGATGTAGCCAAATTGGGGATTGCAGAGTATAACAGTCAGTGC
CGAGCAATTGTGATGCGATACTCTACTGAATGGAAGTCTACTATTACCAGACTTGGCCGA
TGGATTGACTTTGACAATGACTACAAAACTCTGTATCCACAATTCATGGAATCTGTTTGG
TGGATCTTCAAACAACTCTATGATAAAGGCCTTGTTTATAGAGGTGTGAAAGTCATGCCC
TTCTCCACTGCATGCAATACTCCACTCTCCAACTTTGAATCTCACCAGAATTACAAGGAT
GTTCAAGATCCTTCAATATTTGTAACTTTCCCTTTGGAGGAAGATGAAAATATTTCTTTG
GTTGCCTGGACAACTACTCCCTGGACTCTTCCTAGTAACCTTGCCCTGTGTGTTAATCCC
GACTTGCAATATGTGAAGATTAAAGATTCTGTCAGAGGAAAATTACTCATTTTAATGGAA
GCCAGATTATCAGCCCTCTATAAATCGGAGAGTGACTATGAGATCCTTGAAAGATTTCCT
GGTGCCTCTCTCAGAGGCAAGAAATACCGGCCCCTGTTTGACTATTTTGTAAAGTGTAAA
GAGAGTGGTGCTTTTACTGTGCTTGTGGACAACTATGTGAAAGAGGAAGAAGGCACTGGG
ATTGTACACCAAGCTCCTTACTTTGGTGCTGACGATTATCGGGTCTGTATGGATTTCAAC
ATCATTCAGAAAGACTCTCTCCCTATTTGCCCTGTGGATGCCTCAGGCTGTTTTACAGCT
GAAGTGACAGATTTTGCAGGACAGTATGTGAAGGATGCTGACAAAAATATCATCAAGACT
CTAAAGGAACAAGGTCGACTTCTTGTTGCCAGCACCTTCACCCATAGCTACCCTTTTTGT
TGGAGGTCAGACACTCCACTCATTTACAAAGCAGTGCCTAGCTGGTTCGTTAGGGTGGAG
CACATGGTGGATCAGCTGCTGAGGAACAATGACCTGTGTTACTGGGTCCCAGAGTTTGTG
CGAGAAAAGCGATTTGGAAATTGGCTGAAAGATGCACGTGACTGGGCAATTTCCAGAAAC
AGATACTGGGGCACTCCTATCCCACTGTGGGTCAGCAGTGACTTCGAGGAGGTAGTATGT
ATTGGGTCAATAGCAGAACTGGAAGAACTATCAGGAACAAAGATCTCAGATCTCCACAGA
GAGAGCATTGACCATCTGACCATTCCTTCACGCTGTGGAAAGGGATTGTTGCATCGTGTC
TCTGAAGTGTTTGACTGTTGGTTCGAGAGTGGCAGCATGCCATATGCTCAAATTCATTAT
CCATTTGAAAACAAGAGGGAGTTTGAGGATGCATTTCCTGCAGACTTCATTGCTGAAGGC
ATTGACCAAACCAGAGGATGGTTTTACACCTTGCTGGTGCTAGCCACATCTCTCTTTGGA
CGGCCACCATTCAAAAATGTGATTGTGAATGGACTTGTCCTGGCAAGTGATGGTCAAAAA
ATGAGCAAACGCAAAAAGAATTATCCAGACCCACTTTCAGTAATTGATAAATATGGTGCT
GATGCCCTCAGATTATATCTGATTAACTCCCCTGTGGTGAGAGCAGAAAACCTTCGCTTT
AAGGAAGAGGGTGTCCGAGATGTCCTGAAGGATGTACTGCTCCCTTGGTACAATGCCTAT
CGCTTCTTCATCCAGAACGTCCTAAGGCTACAGAAGGAAGAAGAAGTGGAATTCCTTTAC
AACGAGAACATGGTTAAAGAAAGTACCAACATCACAGACCGGTGGGTCCTGTCCTTTATG
CAGTCGCTCGTTGGGTTCTTTGAGACCGAAATGGCAGCTTACAGGCTCTATACTGTGGTT
CCTCGCCTGGTCAAGTTTGTGGATATTTTGACCAATTGGTATGTTCGGATGAACCGTAGA
AGATTAAAGGGTGAAAATGGAGTAGAGGATTGTGTTAAGGCCCTGGAGACCTTGTTTAGT
GTTCTGCTGTCTTTGTGCAGACTTATGGCCCCCTATACCCCTTTTCTTACTGAATTGATG
TATCAGAATCTGAAGACACTGATTGACCCTGTTTCTGTCCAGGACAAGGACACATTCAGT
ATTCACTACCTCATGCTGCCCCATGTTCGTGAGGAATTGATCGACAAGAAAACTGAGAGT
GCAGTATCTAGAATGCAGTCTGTGATTGAACTTGGCCGAGTGATTCGAGACCGCAAAACT
ATTCCAATAAAGTATCCTTTGAAAGAAATTGTTGTTATCCATCAAGATCAGGAAGCTCTT
AATGAAGTTAAGTCTTTGGAGAAATATATCATTGAGGAATTGAATGTTCGAAAAGTTACA
TTATCTACAGATAAAAACAAGTATGGCGTTCGCCTAAGGGCAGAGCCAGATCACATGGTC
CTGGGGAAGCGTCTGAAAGGAGCTTTCAAGATGGTAATGACATCCATCAAACAGCTGAGC
AATGAGGAGCTGGAGCGGTTCCAGGAAAATGGGACCATTGTTGTGGAAGGCCATGAATTG
CATGAAGAAGATATCCGTCTCATATACACCTTTGATCAGGCAACAGGTGGAACAACACAG
TTTGAAGCACACTCAGATGCCCAGGTTTTGGTTCTCTTAGATGTCACCCCTGACCAGTCA
ATGGTGGATGAAGGAATGGCTCGGGAAGTCATCAATCGTATCCAGAAACTTCGCAAAAAG
TGTAATCTGGTTCCAACTGATGAAATAACAGTTTATTATAAAGCAACTTCTGAGGGAAAA
TATCTGAATAATGTTATCGAAAGCCACACAGACTTCATATTTGCTACCATAAAGTCTCCT
TTGAAACCATATCCAGTTCCTATATCGGATGAAATACTTATTCAAGAAAAAATGCAGTTA
AAAGGGTCTGACCTGGAAATTACACTCACCAAAGGATCTTCCACGCATGGCCCTGCTTGT
GCATATGTCAATCTTAACATTTGTACAAATGGCAGTGAGCAAGGTGGAGTATTACTTCTG
GAAAATCCAAAAGGAGATAATAGGTTGGACCTTGTAAAACTGAAGAATGTTGTTACTAGC
ATTTTTGGTGTAAAAAATACAGAGCTGGCTGTCCTCCTTGGTGAAACAGAAATAAAAAAC
CAAACCAACTTACTGAATCTTAGTGGGAAAACACTGTGTGTGACTGCAGGATCAGCGCTG
TCTGTGGTGGACAGTCCTAGTACTCTTCTCTGTCAGTACATCAACCTACAGCTCTTGAAT
GCAGATCCACAAGAGTGTTTAATGGGAACAGTAGGCACTCTTCTGCTTGAAAATCCACTT
GGACAGAATGGGCTTACCCACCAAGGTCTTCTGTATGAAGCTGCCAAGATGTTTGGCCTC
CGGAGCAGGAAGCTAAAGCTGTTTCTGAATGAGACTCAAACAGAAGAAATTACAGAAGAA
ATCCCTATGAAGACTTTGAATACGAAGACTGTGTATGTTTCTGTGTTACCAACTACAGCA
GACTTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 1262 |
| Molecular Weight
| 144642.0 |
| Theoretical pI
| 5.92 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>IARS protein
MVQQVPENISFPAEEEKILQFWSDFNCFQECLKQSKHRPKFTFYDGPPFATGLPHYGHIL
AGTIKDIVTRYAHQSGFHVDRRFGWDCHGLPVEYEIDKTLGIRGPEDVAKLGIAEYNSQC
RAIVMRYSTEWKSTITRLGRWIDFDNDYKTLYPQFMESVWWIFKQLYDKGLVYRGVKVMP
FSTACNTPLSNFESHQNYKDVQDPSIFVTFPLEEDENISLVAWTTTPWTLPSNLALCVNP
DLQYVKIKDSVRGKLLILMEARLSALYKSESDYEILERFPGASLRGKKYRPLFDYFVKCK
ESGAFTVLVDNYVKEEEGTGIVHQAPYFGADDYRVCMDFNIIQKDSLPICPVDASGCFTA
EVTDFAGQYVKDADKNIIKTLKEQGRLLVASTFTHSYPFCWRSDTPLIYKAVPSWFVRVE
HMVDQLLRNNDLCYWVPEFVREKRFGNWLKDARDWAISRNRYWGTPIPLWVSSDFEEVVC
IGSIAELEELSGTKISDLHRESIDHLTIPSRCGKGLLHRVSEVFDCWFESGSMPYAQIHY
PFENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATSLFGRPPFKNVIVNGLVLASDGQK
MSKRKKNYPDPLSVIDKYGADALRLYLINSPVVRAENLRFKEEGVRDVLKDVLLPWYNAY
RFFIQNVLRLQKEEEVEFLYNENMVKESTNITDRWVLSFMQSLVGFFETEMAAYRLYTVV
PRLVKFVDILTNWYVRMNRRRLKGENGVEDCVKALETLFSVLLSLCRLMAPYTPFLTELM
YQNLKTLIDPVSVQDKDTFSIHYLMLPHVREELIDKKTESAVSRMQSVIELGRVIRDRKT
IPIKYPLKEIVVIHQDQEALNEVKSLEKYIIEELNVRKVTLSTDKNKYGVRLRAEPDHMV
LGKRLKGAFKMVMTSIKQLSNEELERFQENGTIVVEGHELHEEDIRLIYTFDQATGGTTQ
FEAHSDAQVLVLLDVTPDQSMVDEGMAREVINRIQKLRKKCNLVPTDEITVYYKATSEGK
YLNNVIESHTDFIFATIKSPLKPYPVPISDEILIQEKMQLKGSDLEITLTKGSSTHGPAC
AYVNLNICTNGSEQGGVLLLENPKGDNRLDLVKLKNVVTSIFGVKNTELAVLLGETEIKN
QTNLLNLSGKTLCVTAGSALSVVDSPSTLLCQYINLQLLNADPQECLMGTVGTLLLENPL
GQNGLTHQGLLYEAAKMFGLRSRKLKLFLNETQTEEITEEIPMKTLNTKTVYVSVLPTTA
DF
|
| External Links |
|---|
| GenBank ID Protein
| AAI51485.1 |
| UniProtKB/Swiss-Prot ID
| A7MBC5 |
| UniProtKB/Swiss-Prot Entry Name
| A7MBC5_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC151484 |
| GeneCard ID
| IARS1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
