| Identification |
|---|
| BMDB Protein ID
| BMDBP02492 |
| Secondary Accession Numbers
| None |
| Name
| ADP-ribosylation factor GTPase-activating protein 2 |
| Synonyms
|
Not Available
|
| Gene Name
| ARFGAP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ARF GTPase activator activity |
| Specific Function
| GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 15 |
| Locus
| Not Available |
| SNPs
| ARFGAP2 |
| Gene Sequence
|
>1563 bp
ATGGCGGCCGAGCCTAACAAGACCGAGATCCAGACGTTTTTTAAGAGGCTTCGCGCAATT
CCGACCAACAAGGCCTGCTTCGACTGTGGCGCTAAGAATCCGAGTTGGGCCAGCATCACG
TACGGTGTTTTTCTGTGCATTGACTGCTCCGGGGTGCATCGCTCCCTGGGCGTCCATCTC
AGCTTCATCAGGTCCACAGAGTTGGATTCCACCTGGAGCTGGTTCCAGCTGAGGTGTATG
CAGGTCGGCGGGAATGCCAATGCGACAGCCTTCTTCCGCCAACATGGATGCACAGCCAAT
GATGCTAACACCAAGTATAACAGTCGAGCTGCCCAGATGTACCGAGAGAAGATCCGGCAG
CTGGGCAGCGCGGCCCTGGCTCGGCATGGCACTGATCTTTGGACAGACAGTGTGAGTACT
GCTCCCAGTCACTCCCCAGAGAAGAAGGAGTCCGATTTCTTCTTGGAACACACTCAACCC
CCTGCCTGGAATGCACCAGTCACCGACCTGTCAGAGACCCAGCAGCCAGCCCCATCTGCA
GAGAGCAGTGGCCTGGCACAGCCGGAGCATGGCCCCAACATGGACCTGCTTGGCACCTCA
CCCAAAGCCTCTCTGGAACCGAAAACCTCCCTCATTGGCAAGAAGAAGCCAGCAGCAGCG
AAGAAGGGGCTGGGTGCCAAGAAGGGCCTAGGGGCCCAGAAGGTGAGCAGCCAGAGTTTC
AGCGAGATTGAGCGGCAGGCCCAGGTGGCAGAGAAGCTCCGTGAGCAGCAGGTGGCTGAT
GCCAAGAAGCAGGCCGAGGAGTCCATGGTTGCCTCCATGCGTCTGGCCTACCAGGAGCTC
CAGATTGACCGTAAGAAGGAGGAGAAGAAGCTACAGAACCTGGAAGGAAAGAAGCGAGAG
CAGGCCGAGAGGTTGGGCATGGGACTGGTGTCCCGAAGCTCCGTCTCGCACTCGGTGCTG
TCTGAGATGCAGGTGATCGAGCAGGAAACCCCAGTGAGTGCCAAGTCCTCCCGCTCGCAG
CTGGACTTATTTGACGACGTTGGCACCTTCGCCTCTGGGCCTCCAAAGTACAAGGACAAC
CCCTTCTCCTTGGGGGAGAGTTTCGGTTCCCGCTGGGATACGGACACTGCCTGGGGTATG
GACAGGATGGAGGAGAAGGAGCCGGAAGTGACCGTTTCCAGCATCCGGCCCGTTTCAGAA
AGAGTCACCAACCGGAGGGAAGTGGAGAGCCGGAGCTCGGGCCTGGAGTCGAGTGAAGCA
CGTCAGAAATTTGCAGGAGCTAAAGCCATCTCCTCCGACATGTTCTTCGGGCGGGAGGTG
GATACTGAGTATGAAGCCAGGTCCCGGCTCCAGCAGCTCTCGGGCAGCAGCGCCATCAGC
TCGTCAGACCTCTTCGGGGACGTGGATGGAGCTCATGGAGCAGGCAGCGTGTCCCTGGGG
AATGTGCTGCCCACGGCTGACATCGCCCAGTTTAAGCAGGGCGTCAAGTCTGTGGCCGGG
AAGATGGCCGTGCTGGCCAATGGCGTGATGAACTCTTTGCAGGATCGCTACGGTTCCTAC
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 520 |
| Molecular Weight
| 56758.0 |
| Theoretical pI
| 8.13 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>ADP-ribosylation factor GTPase-activating protein 2
MAAEPNKTEIQTFFKRLRAIPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHL
SFIRSTELDSTWSWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQ
LGSAALARHGTDLWTDSVSTAPSHSPEKKESDFFLEHTQPPAWNAPVTDLSETQQPAPSA
ESSGLAQPEHGPNMDLLGTSPKASLEPKTSLIGKKKPAAAKKGLGAKKGLGAQKVSSQSF
SEIERQAQVAEKLREQQVADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKRE
QAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKDN
PFSLGESFGSRWDTDTAWGMDRMEEKEPEVTVSSIRPVSERVTNRREVESRSSGLESSEA
RQKFAGAKAISSDMFFGREVDTEYEARSRLQQLSGSSAISSSDLFGDVDGAHGAGSVSLG
NVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY
|
| External Links |
|---|
| GenBank ID Protein
| ABM06074.1 |
| UniProtKB/Swiss-Prot ID
| A1L520 |
| UniProtKB/Swiss-Prot Entry Name
| ARFG2_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT029807 |
| GeneCard ID
| ARFGAP2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
