| Identification |
|---|
| BMDB Protein ID
| BMDBP00544 |
| Secondary Accession Numbers
| |
| Name
| Glutathione peroxidase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| GPX1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Posttranslational modification, protein turnover, chaperones |
| Specific Function
| Protects the hemoglobin in erythrocytes from oxidative breakdown. |
| Pathways
|
Not Available
|
| Reactions
|
| 2 Glutathione + Hydrogen peroxide → Oxidized glutathione +2 Water |
details
|
| 15(S)-HPETE + 2 Glutathione → 15(S)-HETE + Oxidized glutathione + Water |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| Not Available |
| SNPs
| GPX1 |
| Gene Sequence
|
>618 bp
ATGTGCGCCGCTCAGCGCTCGGCGGCCGCCCTGGCGGCGGCAGCCCCGCGCACAGTGTAC
GCCTTCTCCGCGCGCCCTCTGGCCGGCGGGGAGCCCTTCAACCTGTCCTCCCTGCGGGGC
AAGGTGCTGCTCATTGAGAACGTAGCATCGCTCTGAGGCACAACGGTGCGGGACTACACC
CAGATGAATGACCTGCAGCGGCGCCTTGGACCCCGGGGCCTGGTCGTGCTCGGCTTCCCC
TGCAACCAGTTTGGGCATCAGGAAAACGCCAAGAACGAGGAGATCCTGAATTGCCTGAAG
TACGTCCGACCAGGCGGCGGGTTCGAGCCCAACTTTATGCTCTTCGAAAAGTGCGAGGTG
AATGGCGAGAAGGCGCATCCGCTCTTCGCCTTCCTTCGGGAGGTTCTGCCCACGCCAAGT
GACGACGCCACTGCTCTCATGACCGACCCTAAGTTCATCACCTGGTCCCCGGTGTGCCGC
AACGACGTCTCCTGGAACTTCGAGAAGTTCCTGGTGGGCCCAGACGGTGTGCCCGTGCGC
AGGTACAGCCGCCGCTTTCTGACCATCGACATCGAGCCTGACATTGAAACCCTGCTGTCC
CAGGGGGCCTCTGCCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 205 |
| Molecular Weight
| 22659.0 |
| Theoretical pI
| 7.25 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Glutathione peroxidase 1
MCAAQRSAAALAAAAPRTVYAFSARPLAGGEPFNLSSLRGKVLLIENVASLUGTTVRDYT
QMNDLQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNCLKYVRPGGGFEPNFMLFEKCEV
NGEKAHPLFAFLREVLPTPSDDATALMTDPKFITWSPVCRNDVSWNFEKFLVGPDGVPVR
RYSRRFLTIDIEPDIETLLSQGASA
|
| External Links |
|---|
| GenBank ID Protein
| CAB40806.1 |
| UniProtKB/Swiss-Prot ID
| P00435 |
| UniProtKB/Swiss-Prot Entry Name
| GPX1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| X13684 |
| GeneCard ID
| GPX1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
